观察小儿过敏性咳嗽与肺炎支原体感染的相关性及大环内酯类药物的疗效

Observation on Correlation Between Allergic Cough and Mycoplasma Pneumoniae Infection in Children and Efficacy of Macrolides

目的:分析探究小儿过敏性咳嗽、肺炎支原体感染之间的相关性,探究大环内酯类药物的应用效果。方法:选取2020年1-12月日照市莒县人民医院收治的小儿过敏性咳嗽(观察组)、肺炎支原体感染(对照组)患儿各50例展开对照研究。比较两组患儿MP-IgM阳性检测率、总IgE检测数值、血清嗜酸性粒细胞数值评估结果、治疗有效率评估及不良反应发生概率,结果:观察组患儿MP-IgM阳性检出率明显高于对照组,观察组与对照组总IgE检测数值、血清嗜酸性粒细胞数值对比差异显著,观察组临床治疗有效率高于对照组,观察组不良反应发生率低于对照组,差异均有统计学意义(P<0.05)。结论:小儿过敏性咳嗽、肺炎支原体感染之间具有密切联系,于治疗期间应用大环内酯类药物具有较高的安全性和有效性,对于改善临床症状具有积极意义,在临床上具有借鉴以及推广价值。

Objective:To analyze the correlation between allergic cough and Mycoplasma pneumoniae infection in children,and to explore the application effect of macrolides.Methods:This control study was conducted from January 2020 to December 2020 among 50 children with allergic cough(observation group)and 50 children with Mycoplasma pneumoniae infection(control group).The positive detection rate of MP-IgM,total IgE value,serum eosinophil count,evaluation of effective treatment rate and probability of adverse reactions of children in the two groups were compared.Results:The positive detection rate of MP-IgM in the observation group was remarkably higher than that in the control group.There were significant differences in total IgE value and serum eosinophil count between the observation group and the control group.The effective rate of clinical treatment in the observation group was higher than that in the control group,and the probability of adverse reactions in the observation group was remarkably lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion:There is a close relationship between allergic cough and Mycoplasma pneumoniae infection in children.The application of macrolides during treatment has high safety and effectiveness,has positive significance for improving clinical symptoms,and has reference and popularization value in clinic.