颈动脉及下肢动脉粥样硬化与冠心病相关性的研究进展

Research progress of correlation of carotid artery and lower limb atherosclerosis with coronary heart disease

冠状动脉疾病(CAD)发病率逐年升高,及早发现CAD及对其不良预后高危人群加以早期干预,能够改善患者预后。颈动脉及下肢动脉粥样硬化与CAD的发生发展及预后之间存在重要关系。联合评价颈动脉和下肢动脉粥样硬化不仅能够辅助识别CAD并反映其严重程度,还能够预测CAD患者及心肌血运重建患者术后发生不良心血管事件的风险,以完善高风险人群二级预防措施。血管超声是无创评价动脉粥样硬化的主要手段。本文就颈动脉、下肢动脉粥样硬化以及两者的联合评价在CAD诊断和预后中的作用及研究进展进行综述。

The incidence of coronary artery disease(CAD)is increasing yeaRby year.Early detection of CAD and early intervention in high risk groups can improve the prognosis of patients.There is an important relationship between carotid as well as loweRlimb atherosclerosis and the occurrence,development and prognosis of CAD.Combined evaluation of carotid and loweRlimb atherosclerosis can not only assist in the identification of CAD and reflect its severity,but also predict the risk of adverse cardiovasculaRevents in CAD patients and those with myocardial revascularization,thereby improving secondary prevention measures in high-risk populations.VasculaRultrasound is the main method of noninvasive evaluation of atherosclerosis.This papeRreviewed the role,research progress of carotid and loweRlimb atherosclerosis,and theiRcombined evaluation in diagnosis and prognosis of CAD.