摘要
目的 观察针刀松解术联合星状神经节阻滞治疗颈性高血压的疗效。方法 采用随机数字表法将136例颈性高血压患者分为实验组和对照组,每组68例。对照组给予星状神经节阻滞治疗,实验组在对照组治疗基础上加用针刀松解术。比较2组治疗总有效率和治疗前后颈椎功能障碍指数量表(NDI)评分、视觉模拟评分法(VAS)评分、血流动力学指标[动脉血管内径(VD)、平均血流速度(MFV)、动脉收缩期血流量峰值(PSV)和动脉舒张末期血液流速(EDV)]水平、血压、血清炎性因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)]水平、简易智力状态检查量表(MMSE)评分。结果 治疗后,2组NDI评分、VAS评分、舒张压、收缩压均低于治疗前,且实验组低于对照组,差异有统计学意义(P<0.05)。2个疗程后、治疗结束后,2组血清TNF-α、IL-6、IL-1β水平均低于治疗前,且实验组水平低于对照组,差异有统计学意义(P<0.05)。治疗后,2组MMSE评分均低于治疗前,但实验组MMSE评分高于对照组,差异有统计学意义(P<0.05)。治疗后,2组VD、MFV、PSV、EDV均高于治疗前,且实验组高于对照组,差异有统计学意义(P<0.05)。实验组治疗总有效率为98.53%,高于对照组的85.29%,差异有统计学意义(P<0.05)。结论 针刀松解术联合星状神经节阻滞治疗颈性高血压效果较好,可有效降低患者血清炎性因子、血压及血流动力学指标水平,减轻颈椎功能障碍程度,保护患者认知功能。
Objective To observe the effect of acupotomy release combined with stellate ganglion block in the treatment of patients with cervical hypertension. Methods A total of 136 patients with cervical hypertension were divided into experimental group(n=68) and control group(n=68) according to random number table method. The control group was treated with stellate ganglion block, and the experimental group was treated with acupotomy release on the basis of the control group. The total effective rate and the Neck Disability Index(NDI) score, Visual Analogue Scale(VAS) score, hemodynamic indexes [vessel diameter(VD), mean blood flow velocity(MFV), peak systolic blood flow(PSV) and end diastolic blood flow(EDV)], blood pressure, serum inflammatory factors [tumor necrosis factor-α(TNF-α), interleukin-6(IL-6), interleukin-1β(IL-1β)] and mini-mental state examination(MMSE) score were compared before and after treatment between two groups. Results After treatment, the NDI score, the VAS score, diastolic blood pressure and systolic blood pressure in both groups were significantly lower than those before treatment(P<0.05), and these indexes in the experimental group were significantly lower than those in the control group(P<0.05). After 2 courses of treatment and at the end of treatment, the levels of serum TNF-α, IL-6 and IL-1β in both groups decreased significantly(P<0.05), and the levels of these indexes in the experimental group were significantly lower than those in the control group(P<0.05). After treatment, the MMSE score in both groups significantly decreased, but the MMSE score in the experimental group was significantly higher than that in the control group( P < 0. 05). After treatment,VD,MFV,PSV and EDV in both groups significantly increased,and these indexes in the experimental group were significantly higher than those in the control group( P < 0. 05). The total effective rate of the experimental group was 98. 53%,which was significantly higher than 85. 29% of the control group( P < 0. 05). Conclusion Acupotomy release combined with stellate ganglion block is effective in the treatment of patients with cervical hypertension,which can effectively reduce the levels of serum inflammatory factors,blood pressure and hemodynamic indexes,alleviate the degree of cervical dysfunction,and protect the cognitive function of patients.
作者
王建华
WANG Jianhua(Department of Anesthesiology,Qinhuangdao City Hospital of Traditional Chinese Medicine in Hebei Province,Qinhuangdao,Hebei,066004)
出处
《实用临床医药杂志》
CAS
2022年第4期84-88,共5页
Journal of Clinical Medicine in Practice
基金
河北省秦皇岛市重点研发计划科技支撑项目(201902A063)。
关键词
针刀松解术
星状神经节阻滞
颈性高血压
认知功能
血流动力学
acupotomy release
stellate ganglion block
cervical hypertension
cognitive function
hemodynamics