摘要
目的分析第三腰椎横突综合征患者的肌骨超声表现及与Oswestry功能障碍指数(ODI)的相关性。方法回顾性分析2019年1月—2021年2月在河北省中医院就诊的121例第三腰椎横突综合征患者的临床资料(观察组),另取同期该院健康体检者50例作为对照组。治疗前后采用肌骨超声对患者进行检查;并采用ODI评价患者腰椎功能,分析肌骨超声表现与ODI评分的相关性。结果治疗前,观察组肌骨超声评分、ODI评分高于对照组(P<0.05);治疗后观察组患者肌骨超声评分、ODI评分降低(P<0.05)。观察组治疗前后肌骨超声评分与ODI评分均呈正相关(r=0.735和0.681,P=0.009和0.018)。观察组治疗前后血清IL-6、IL-10、TNF-α水平均高于对照组(P<0.05);治疗后观察组血清IL-6、IL-10、TNF-α水平低于治疗前(P<0.05)。逐步多因素Logistic回归分析结果表明,肌骨超声评分[OR=1.881(95%CI:1.239,2.856)]、ODI评分[OR=1.848(95%CI:1.246,2.740)]、IL-6[OR=1.818(95%CI:1.234,2.681)]、IL-10[OR=1.868(95%CI:1.226,2.847)]、TNF-α[OR=1.837(95%CI:1.224,2.756)]是影响第三腰椎横突综合征患者发病的独立危险因素(P<0.05)结论第三腰椎横突综合征患者的肌骨超声表现与ODI评分呈正相关,肌骨超声评分、ODI评分、IL-6、IL-10、TNF-α是影响第三腰椎横突综合征患者发病的独立危险因素。
Objective To analyze the correlation between musculoskeletal ultrasound findings and Oswestry Disability Index(ODI)in the third lumbar transverse process syndrome.Methods The clinical data of 121 patients with the third lumbar transverse process syndrome admitted to Hebei Hospital of Traditional Chinese Medicine from January 2019 to February 2021 were analyzed as the observation group,and 50 healthy people who underwent physical examination in the hospital during the same period were set as the control group.The musculoskeletal ultrasound was performed before and after the treatment,and ODI was used to assess the lumbar function of patients before and after the treatment.The correlation between ultrasound findings and ODI was analyzed.Results The musculoskeletal ultrasound and ODI scores were higher in the observation group than those in the control group before the treatment(P<0.05).After the treatment,the musculoskeletal ultrasound and ODI scores were lowered in the observation group(P<0.05).The musculoskeletal ultrasound score was positively correlated with the ODI score both before and after the treatment(r=0.735 and 0.681,P=0.009 and 0.018,respectively).The serum levels of interleukin(IL)-6,IL-10 and tumor necrosis factor-α(TNF-α)in the observation group were higher than those in the control group both before and after the treatment,while they were lower after the treatment relative to those before the treatment in the observation group(P<0.05).The multivariable Logistic regression analysis revealed that the musculoskeletal ultrasound score[OR=1.881(95%CI:1.239,2.856)],ODI score[OR=1.848(95%CI:1.246,2.740)],IL-6[OR=1.818(95%CI:1.234,2.681)],IL-10[OR=1.868(95%CI:1.226,2.847)],and TNF-α[OR=1.837,(95%CI:1.224,2.756)]were factors affecting the development of the third lumbar transverse process syndrome(P<0.05).Conclusions There is a positive correlation between the musculoskeletal ultrasound findings and the ODI score in patients with the third lumbar transverse process syndrome.The musculoskeletal ultrasound score,ODI score,and the levels of IL-6,IL-10 and TNF-αare independent factors influencing the development of the third lumbar transverse process syndrome.
作者
刘凤飞
刘哲
麻继红
张春东
吴菲
Feng-fei Liu;Zhe Liu;Ji-hong Ma;Chun-dong Zhang;Fei Wu(Department of Function Test,Hebei Hospital of Traditional Chinese Medicine,Shijiazhuang,Hebei 050011,China;Department of Diagnostic Ultrasound,Linxi Hospital of Kailuan General Hospital,Tangshan,Hebei 063104,China)
出处
《中国现代医学杂志》
CAS
北大核心
2022年第4期79-83,共5页
China Journal of Modern Medicine
基金
河北省中医药管理局科研计划项目(No:2021014)。