咖啡的摄入与2型糖尿病

Coffee consumption and type 2 diabetes mellitus

适量饮用咖啡有益于人体健康,然而,喝咖啡对糖尿病患者血糖和胰岛素水平的影响目前仍存在争议。已有许多流行病学和临床试验研究了咖啡的频繁饮用与2型糖尿病发病风险之间的关系。事实上,咖啡是人类饮食中绿原酸的主要来源,绿原酸和其他酚类化合物通过干扰葡萄糖转运抑制葡萄糖的吸收并增加胰岛素的敏感性。然而,短期试验证实了由于咖啡因的存在,大量饮用咖啡对机体健康的损害,咖啡因会损害葡萄糖耐量且降低胰岛素的敏感性。我们综述了饮用咖啡对健康的影响,重点是咖啡的摄入与2型糖尿病之间的关系,发现适量饮用咖啡对健康有长期的好处和积极的影响。

Moderate coffee consumption has a beneficial health effect on the human body.However,there are controversial opinions of consuming coffee on blood glucose and insulin levels in patients with diabetes mellitus.Many epidemiological and clinical trials have studied the relationship between frequent drinking of coffee and the risk of type 2 diabetes.The association between the frequent consumption of coffee and the risk of type 2 diabetes has been studied through epidemiologic and clinical studies.In fact,coffee is a major source of chlorogenic acids in the human diet,its presence and other phenolic compounds in coffee plays a role in inhibiting glucose absorption via interference with glucose transporters and increasing insulin sensitivity.However,short-term trials confirm the detrimental effects of heavily drinking coffee due to the presence of caffeine.Caffeine has been found to impair glucose tolerance and decrease insulin sensitivity.In this review,we concluded the health effects of coffee consumption,and emphasize on the relationship between the consumption of coffee and the development of type 2 diabetes.It is suggested that moderate consumption of coffee has long-term benefits and positive health effects.