摘要
The development of fluorophores emitting in the near-infrared spectral window has gained increased attention given their suitable features for biological imaging.In this work,we have optimised a general and straightforward synthetic approach to prepare a small library of near-infrared-emitting C-bridged nitrobenzodiazoles using commercial precursors.C-bridged benzodiazoles have low molecular weight and neutral character as important features that are not common in most nearinfrared dyes.We have investigated their fluorescence response in the presence of a wide array of 60 different biomolecules and identified compound 3i as a potential chemosensor to discriminate between Fe2+and Fe^(3+)ions in aqueous media.
基金
funding from Medical Research Scotland(Sam Benson:879-2015)
ERC Consolidator Grant(DYNAFLUORS,Marc Vendrell:771443)
supported by National Research Foundation funded by the Ministry of Science,ICT&Future Planning,South Korea(Jun-Seok Lee:NRF2018M3A9H4079286,NRF-2020R1A2C2004422).