儿童传染性单核细胞增多症并发症特征

Characteristics of Complications of Infectious Mononucleosis in Children

目的:探讨儿童传染性单核细胞增多症(infectious mononucleosis,IM)并发症特征。方法:回顾性分析2018年1月-2020年1月青海省妇女儿童医院就诊的80例IM患儿的临床资料。根据患儿年龄分为不同年龄段。所有患儿均予以抗病毒治疗及对症治疗。分析80例IM患儿并发症发生情况,比较不同年龄段IM患儿并发症发生情况。结果:80例患儿出现并发症者60例(75.00%),累及1个系统者35例,累及2个系统者24例,累及3个系统者1例。发生的并发症有呼吸系统、循环系统、血液系统、神经系统、消化系统、泌尿系统并发症及肝功能异常、眼睑水肿。最常见的并发症为呼吸系统、循环系统并发症及肝功能异常,发生率分别为36.67%、35.00%、30.00%。3个月~3岁,4~6岁,7~14岁IM患儿的循环系统、肝功能异常发生率随着年龄的增长而明显升高(P<0.05)。结论:儿童IM的并发症发生率高,可累及各个系统组织,以呼吸系统、循环系统并发症及肝功能异常最为常见,且年龄越大,循环系统并发症、肝功能异常发生率越高,临床上应予以重视。

Objective:To explore the characteristics of complications of infectious mononucleosis(IM)in children.Method:Clinical data of 80 children with IM admitted to Qinghai Women and Children’s Hospital from January 2018 to January 2020 were retrospectively analyzed.According to the age of children,they were divided into different age groups.All the children were given the antiviral therapy and symptomatic treatment.The occurrence condition of complications in 80 children with IM was analyzed,and the occurrence condition of complications in IM children of different ages was compared.Result:Among the 80 cases,60 cases(75.00%)had complications,35 cases involved 1 system,24 cases involved 2 systems,and 1 case involved 3 systems.Complications of respiratory system,circulatory system,blood system,nervous system,digestive system,urinary system,abnormal liver function,eyelid edema were occured.The most common complications were respiratory system,circulatory system complications and abnormal liver function,with incidence of 36.67%,35.00% and 30.00% respectively.The incidence of circulatory system and abnormal liver function in IM children aged 3 months-3 years,4-6 years and 7-14 years increased significantly with the increase of age(P<0.05).Conclusion:The incidence of complications of children with IM is high,which can affect various system tissues.Complications of the respiratory system and circulatory system and abnormal liver function are the most common.The older the children are,the higher the incidence of circulatory system complications and abnormal liver function,the clinical should be paid attention to it.