糖尿病足患者发生感染的影响因素分析

Analysis of Influencing Factors of Infection in Diabetic Foot Patients

目的:探讨糖尿病足患者发生感染的影响因素分析。方法:选取2019年2月-2020年2月福建医科大学附属第二医院收治的185例糖尿病足患者进行研究,根据感染情况分为感染组(69例)、非感染组(116例)。收集患者临床资料,分析两组临床特点,采用多因素Logistic回归模型分析糖尿病足发生感染的危险因素。结果:本次研究185例患者,其中69例(37.30%)发生感染,Wagner分级:1级17例,2级23例,3级20例,4级9例。单因素分析结果显示,两组性别、体质量指数(BMI)、病程、高血压、冠心病、高脂血症比较,差异均无统计学意义(P>0.05);感染组年龄、合并血管并发症、合并视网膜病变、溃疡数目≥3个、合并骨髓炎、合并糖尿病肾病、吸烟史占比均高于非感染组,差异均有统计学意义(P<0.05);多因素非条件Logistic回归分析结果显示,年龄、合并血管并发症、合并视网膜病变、溃疡数目≥3个、合并骨髓炎、合并糖尿病肾病、吸烟史均是糖尿病足发生感染的独立危险因素(P<0.05)。结论:在糖尿病足伴有不同程度感染中,临床影响因素较多,临床应针对高危因素采取针对性的预防措施,降低感染率。

Objective:To analyze the influence factors of infection in diabetic foot patients by multivariate regression.Method:A total of 185 patients with diabetic foot admitted to the Second Affiliated Hospital of Fujian Medical University from February 2019 to February 2020 were selected for the study.According to the infection situation,they were divided into the infected group(69 cases)and the non-infected group(116 cases).The clinical data of patients were collected to analyze the clinical characteristics of the two groups,and the risk factors of diabetic foot infection were analyzed by multi-factor Logistic regression model.Result:Among 185 patients in this study,69 cases(37.30%)were infected,Wagner’s classification:17 cases in grade 1,23 cases in grade 2,20 cases in grade 3,and 9 cases in grade 4.Univariate analysis showed that there were no significant differences in gender,body mass index(BMI),course of disease,hypertension,coronary heart disease and hyperlipidemia between the two groups(P>0.05).The age,vascular complications,retinopathy,number of ulcers≥3,osteomyelitis,diabetic nephropathy and smoking history of infected group were higher than those of non-infected group,and the differences were statistically significant(P<0.05).Multi-factor Logistic regression results showed that age,vascular complication,retinopathy,number of ulcers≥3,osteomyelitis,diabetic nephropathy and smoking history were all independent risk factors for diabetic foot infection(P<0.05).Conclusion:In diabetic foot with different degrees of infection,there are many clinical influencing factors,and clinical preventive measures should be taken to reduce the infection rate.