分段稀释滴注与常规脱敏注射抗蛇毒血清对蛇咬伤患者的影响

Effect of Segmented Dilution Instillation and Routine Desensitization Injection of Antivenin on Snakebite Patients

目的:探讨分段稀释滴注与常规脱敏注射抗蛇毒血清对蛇咬伤患者的影响。方法:回顾性选取2020年5月-2021年7月福建医科大学附属龙岩第一医院收治的88例蛇咬伤患者的临床资料。根据给药方式将其分为对照组与观察组,各44例。两组入院后,均予以常规急救措施,对照组给予常规脱敏注射给药方式,观察组给予分段稀释滴注给药方式。比较两组治疗后过敏反应、住院时间及接受程度。结果:观察组过敏反应发生率为11.37%,较对照组的29.54%低(P<0.05)。观察组接受度评分高于对照组,住院时间短于对照组(P<0.05)。结论:分段稀释滴注抗蛇毒血清治疗蛇咬伤患者,可降低过敏反应风险,提高患者给药方式接受度,安全性高,有利于加快患者康复,缩短住院时间,值得推广。

Objective:To investigate the effect of segmented dilution instillation and routine desensitization injection of antivenin on snakebite patients.Method:The clinical data of 88 snakebite patients admitted to Longyan First Hospital Affiliated to Fujian Medical University from May 2020 to July 2021 were retrospectively selected.According to the mode of administration,they were divided into control group and observation group,44 cases in each group.After admission,both groups were given routine emergency measure.The control group was given the mode of administration of routine desensitization injection,and the observation group was given the mode of administration of segmented dilution instillation.Allergic reaction after treatment,hospital stay and acceptance were compared between the two groups.Result:The incidence of allergic reaction in observation group was 11.37%,which was lower than 29.54%in control group(P<0.05).The acceptance score of the observation group was higher than that of the control group,and the hospital stay was shorter than that of the control group(P<0.05).Conclusion:Segmented dilution instillation of antivenin for the treatment of snakebite patients can reduce the risk of allergic reaction,improve the acceptance of the mode of administration for patients,with high safety,help to speed up the recovery of patients and shorten the hospital stay,which is worthy of promotion.