摘要
Pluripotency is recognized as a spectrum of cellular states spanning the na?ve pluripotency established in the preimplantation blastocyst and its transition into primed pluripotency in the postimplantation epiblast cells. The exit from pluripotency is followed by the initiation of gastrulation(Brennan et al., 2001;Nichols and Smith, 2009).
基金
funded by grants from the National Institutes of Health (R01GM129157, R01HD095938, R01HD097268, and R01HL146664)
by contracts from New York State Stem Cell Science (NYSTEM#C35583GG and C35584GG)。
