Delta新冠病毒变异毒株的防控与治疗进展

Progress in prevention and control of Delta coronavirus variant

随着新型冠状病毒在全球范围内的传播,变异株不断出现,其中德尔塔(Delta)毒株因其传播力强、病毒载量高、致病性强等特点迅速成为优势毒株,给全球疫情防控带来了新的挑战,现有疫苗的有效性也大大降低,病毒单链RNA的特点意味着变异仍会持续发生,如何应对变异毒株的流行也成为广泛关注的问题。针对Delta毒株国内外均制定了更加严格的防护与管控策略,与此同时新冠病毒及其变异株的特效药物的研发和变异毒株疫苗的相关研究也取得了进展,这些都为今后应对新冠病毒及其变异毒株的传播提供了更多的参考。本文就国内外针对Delta新冠变异株的防控措施进行总结,并对新冠病毒及其变异株的治疗研究进展进行综述,以期为制定更加科学完善的防控策略提供科学依据。

With the spread of SARS-CoV-2 virus worldwide,mutant strains are constantly emerging.The Delta strain has quickly become the dominant strain because of its powerful transmission,high viral load,and strong pathogenicity.It has brought new challenges to the global epidemic prevention and control,and the effectiveness of the existing vaccines have also been significantly reduced.The single-strand RNA characteristics of the virus mean that the mutation will continue to occur,and how to deal with the prevalence of mutant strains has also become a widespread concern.More stringent protection and control strategies have been developed for Delta strains at home and abroad.At the same time,it has progressed in the research and development of specific drugs and variant vaccines for SARS-CoV-2 virus and its mutant strains,which will provide more references for the future dissemination of SARS-CoV-2 virus and its variant strains.In this paper,we summarized the prevention and control measures of Delta at home and abroad,and reviewed the research progress on the treatment of SARSCoV-2 virus and its mutant strains,in order to provide a scientific basis for formulating more scientific and perfect prevention and control strategies.