垂体后叶素联合宫腔镜下清宫术治疗剖宫产瘢痕妊娠的临床效果

Clinical Effect of Pituitrin Combined with Hysteroscopic Curettage in the Treatment of Cesarean Scar Pregnancy

目的观察垂体后叶素联合宫腔镜下清宫术治疗剖宫产瘢痕妊娠的临床疗效。方法选取2019年7月-2021年7月在我院诊治的78例剖宫产瘢痕妊娠患者为研究对象,采用随机数字表法分为对照组和观察组,各36例。对照组采用双侧子宫动脉栓塞术联合宫腔镜下清宫术治疗,观察组注射垂体后叶素联合宫腔镜下清宫术治疗。比较两组临床手术指标、术后康复指标、生活质量水平以及不良反应发生情况。结果观察组手术时间、术中出血量、住院时间均短于对照组,差异有统计学意义(P<0.05);观察组术后阴道出血时间、月经恢复时间、血人绒毛膜促性腺激素(β-hCG)水平恢复正常时间均短于对照组,差异有统计学意义(P<0.05);两组生活质量评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为8.33%,低于对照组的19.44%,差异有统计学意义(P<0.05)。结论垂体后叶素联合宫腔镜下清宫术治疗剖宫产瘢痕妊娠效果确切,手术时间短、术中出血量少,术后恢复快,可缩短住院时间,促进月经和血β-hCG水平恢复,提高患者生活质量水平,且不良反应少,是一种安全、有效的治疗方案。

Objective To observe the clinical effect of pituitrin combined with hysteroscopic curettage in the treatment of cesarean scar pregnancy.Methods A total of 78 patients with cesarean scar pregnancy diagnosed and treated in our hospital from July 2019 to July 2021 were selected as the research objects and randomly divided into the control group and the observation group,with 36 cases in each group.The control group was treated with bilateral uterine artery embolization combined with hysteroscopic curettage,and the observation group was treated with pituitrin combined with hysteroscopic curettage.The clinical operation indexes,postoperative rehabilitation indexes,quality of life and incidence of adverse reactions were compared between the two groups.Results The operation time,intraoperative blood loss and hospitalization time of the observation group were shorter than those of the control group,and the difference was statistically significant(P<0.05).The postoperative vaginal bleeding time,menstrual recovery time and the recovery time of blood human chorionic gonadotropin(β-hCG)level in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).The quality of life scores of the two groups were higher than those before treatment,and the observation group was higher than the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 8.33%,which was lower than 19.44%in the control group,and the difference was statistically significant(P<0.05).Conclusion Pituitrin combined with hysteroscopic curettage is effective in the treatment of cesarean scar pregnancy,with shorter operation time,less intraoperative blood loss,faster postoperative recovery,shorter hospitalization time,and also can promote the recovery of menstruation and bloodβ-hCG level,improve the quality of life of patients,and less adverse reactions.It is a safe and effective treatment.