摘要
目的:评估tDCS对海洛因成瘾患者的慢性药物渴求及负性情绪的干预效果。方法:以沈阳市8个社区戒毒(康复)中心328例海洛因成瘾的戒毒人员为研究对象,采用随机数字表法将研究对象分为干预组和对照组。干预组连续两周在右侧DLPFC(阳极)和左侧DLPFC(阴极)区域接受7次tDCS治疗,每次持续20 min;对照组采用相同的方法接受假tDCS治疗。在干预前和干预后对两组患者应用吸毒人员一般调查问卷、药物慢性渴求量表及抑郁、焦虑和压力量表-21(DASS-21)进行问卷调查。结果:与对照组相比,经过7次tDCS治疗后,干预组慢性药物渴求量表的5个维度得分下降趋势较为明显(P<0.05),干预组抑郁、焦虑和压力显著降低(P<0.05)。结论:tDCS可作为一种安全、有效的缓解海洛因成瘾者慢性药物渴求及负性情绪的方法。
Objective:To evaluate the intervention effect of tDCS on chronic drug craving and negative emotion of heroin addicts. Methods: A total of 328 heroin addicts in 8 community drug rehabilitation centers in Shenyang were selected as the subjects and randomly divided into intervention group and control group. The intervention group received 7 tDCS treatments in the right DLPFC(anode) and left DLPFC(cathode) area for 20 minutes for two consecutive weeks, while the control group received sham tDCS treatment with the same method. Before and after the intervention, the general questionnaire, chronic drug craving scale and depression, anxiety and stress Scale-21(DASS-21) were used to investigate the two groups. Results: Compared with the control group, after 7 times of tDCS treatment, the scores of five dimensions of chronic drug craving scale in the intervention group decreased significantly(P<0.05), and the depression, anxiety and stress in the intervention group decreased significantly(P<0.05). Conclusion: tDCS can be used as a safe and effective method to relieve chronic drug craving and negative emotions of heroin addicts.
作者
王玮
陈晶莹
WANG Wei;CHEN Jingying(Department of Drug Prohibition,National Police University of China,Shenyang,110035,China)
出处
《中国药物依赖性杂志》
CAS
CSCD
2021年第6期424-427,434,共5页
Chinese Journal of Drug Dependence
基金
“十三五”国家重点研发计划项目(2018YFC0807405)。
