摘要
Objective:The nuclear factor erythroid 2(NFE2)-related factor 2(Nrf2)is associated with doxorubicin(DOX)-induced cardiac injury.It has been reported that microRNA-24-3p(miR-24-3p)may regulate the Keapl by mRNA degradation,whereas Keapl can suppress the activation of Nrf2.However,the role of miR-24-3p in DOX-related cardiotoxicity remains unclear.
基金
This project was supported by National Natural Science Foundation of China(No.80700289)and Medical Research Foundation of Wuhan Municipal Health Commission(No.WX19Q15).
