中国儿科药品常用剂型研究进展及前景分析

Research progress and prospect analysis of common dosage forms of pediatric drugs in China

我国儿科药品剂型较丰富,但是常用药物种类及规格仍无法满足日益增长的用药需求。综述我国儿科药品常用剂型种类及其应用现状,发现儿童常用药物剂型有片剂、颗粒剂、注射剂等,口服剂型所面临的主要问题是口感差、用药依从性低;非口服剂型用药依从性相对较高,但儿童用产品较少,需大力开发。针对各剂型研发所面临的机遇及挑战,未来儿童用药首选剂型仍是口服制剂,但是会向微片、微丸、分散片的形式发展。

China's pediatric drug dosage form is relatively rich,but the types and specifications of commonly used medicines still cannot meet the increasing demand for medicines.The author reviewed the types of commonly used pediatric drugs and their application status in China,and found that the commonly used drug forms for children include tablets,granules,injections,etc.The main problems faced by oral dosage forms are poor taste and low medication compliance;the compliance of non-oral dosage forms medication is relatively high,but there are few products for children,which need to be developed vigorously.In view of the opportunities and challenges faced by the development of various dosage forms,the preferred dosage form for children's medicine in the future will still be oral preparations,but will develop into the form of microtablets,pellets,and dispersible tablets.