糖化血红蛋白监测对糖尿病合并肺结核患者的临床价值分析

Analysis of clinical value of glycosylated hemoglobin monitoring on patients with diabetes mellitus and pulmonary tuberculosis

目的探讨监测糖化血红蛋白水平(Hb A1c)对糖尿病合并肺结核患者的临床价值。方法回顾性分析2234例糖尿病合并肺结核患者的临床资料,根据入院治疗时的HbA1c水平分为血糖控制良好组(HbA1c<8%,826例)与血糖控制不良组(HbA1c≥8%,1408例)。比较两组患者临床资料、病原学药敏结果、影像学特点,分析不同糖化血红蛋白水平的糖尿病合并肺结核患者病原学药敏结果及影像学特点。结果两组性别和年龄比较,差异均有统计学意义(P<0.05)。血糖控制不良组病原学阳性率为81.41%,高于血糖控制良好组的69.56%,差异有统计学意义(P<0.05)。血糖控制不良组空洞率为68.86%,高于血糖控制良好组的51.17%,差异有统计学意义(P<0.05)。结论糖化血红蛋白水平有助于监测和判断糖尿病合并肺结核患者的临床情况。

Objective To discuss the effect of glycosylated hemoglobin(HbA1c)monitoring on patients with diabetes mellitus and pulmonary tuberculosis.Methods The clinical data of 2234 patients with diabetes mellitus and pulmonary tuberculosis were retrospectively analyzed.According to the HbA1c level at admission,they were divided into well control group(HbA1c<8%,826 cases)and poor control group(HbA1c≥8%,1408 cases).The clinical data,pathogenic drug sensitivity results,and imaging characteristics of the two groups were compared,and the pathogenic drug sensitivity results and imaging characteristics of patients with different levels of glycosylated hemoglobin were analyzed.Results There were statistically significant differences in gender and age between the two groups(P<0.05).The pathogenic positive rate 81.41%in the poor control group was higher than 69.56%in the well control group,and the difference was statistically significant(P<0.05).The vacancy rate in the poor control group was 68.86%,which was higher than 51.17%in the well control group,and the difference was statistically significant(P<0.05).Conclusion The level of glycosylated hemoglobin is helpful for monitoring and judging the clinical situation of patients with diabetes mellitus and pulmonary tuberculosis.