摘要
Immunoglobin(Ig)G4-related disease(IgG4-RD)is an immune-mediated fibroinflammatory condition characterized by elevated serum IgG4 levels and multi-organ involvement.The characteristic histological findings of IgG4-RD are dense lymphoplasmacytic infiltration,fibrosis,and massive IgG4 positive plasma cells infiltrating the affected tissues.[1]Previous studies have demonstrated various relapse predictors corresponding to demographic,clinical characteristics,laboratory test results,and treatment agents.However,no study has revealed the risk factors of flares in pathology.This study aimed to ascertain whether the pathological characteristics are related to therapeutic outcomes.
基金
This work was supported by grants from the National Natural Science Foundation of China(Nos.81771757,81771780,82071839)
the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(No.NWB20203346)
Capital’s Funds for Health Improvement and Research(No.2020-2-4017)
Beijing Municipal Science and Technology Commission(No.Z201100005520023)。
