论大黄在慢性肾衰竭中应用

Application of Dahuang(Rhei Radix Et Rhizoma) in Chronic Renal Failure

慢性肾衰竭是慢性肾脏病的终末期阶段,是以病程长、症状繁多、病情复杂为主的临床综合征。近年来,慢性肾衰竭患者发病率不断增加,肾脏疾病已经成为严重危害人类健康与生命的疾病之一。传统中药经验理论丰富、效果力专,且安全性高、不良反应少,现代医学对大黄的研究一直成为焦点。中药大黄作为通腑泄浊之要药,又有下瘀血、主寒热、破症瘕积聚、推陈致新、安和五脏之效。临证治疗慢性肾衰竭时,常以大黄为切入点,通过查阅相关文献,主要从药物功用、炮制之品、名医名家经验、改善肠道菌群、多途径治疗(中成药、保留灌肠、结肠透析、穴位贴敷、中药离子导入、药浴、足浴)等方面对大黄治疗慢性肾衰竭的研究概况进行简要归纳,并总结不足,展望其研究前景,以期明确获得药用角色和配伍使用。

Chronic renal failure is the terminal stage of chronic kidney disease. It is a clinical syndrome with a long course of disease,various symptoms,and complex conditions. In recent years,the incidence of chronic renal failure patients has been increasing,and kidney disease has become one of the diseases that seriously endanger human health and life. Traditional Chinese medicine has the advantages of rich experience and theory,strong effects,high safety,and few adverse reactions. In recent years,modern medical research on Dahuang(Rhei Radix Et Rhizoma)has been the focus. Dahuang(Rhei Radix Et Rhizoma),a traditional Chinese medicine,is an essential medicine to relieve the turbidity and turbidity of the internal organs. It also has the effect of blood stasis,the main body of cold and heat,the accumulation of symptoms and diseases,the improvement of the old and the new,and the effect of calming the five organs. In clinical treatment of chronic renal failure,Dahuang(Rhei Radix Et Rhizoma)is often used as the entry point. Through consulting related literature in recent years,it mainly focuses on the functions of drugs,concocted products,and the experience of famous doctors,improving intestinal flora,and multiple approaches(Chinese patent medicine,retention enema,colon dialysis,acupoint application,traditional Chinese medicine iontophoresis,medicated baths,foot baths,etc.),briefly summarize the research status of the treatment of chronic renal failure,summarize the shortcomings,and look forward to its research prospects,in order to clearly obtain the medicinal role and compatibility.