急诊双定位ESWL联合间苯三酚治疗输尿管结石临床效果

Clinical Effect of Emergency Double Location ESWL Combined With Phloroglucinol in the Treatment of Ureteral Calculi

目的探析输尿管结石患者应用联合方案[双定位体外冲击波碎石术(ESWL)+间苯三酚]的治疗效果及对超敏C-反应蛋白(hs-CRP)水平的影响。方法选取本院2019年1月—2021年2月就诊的200例输尿管结石患者,根据治疗方式分为两组,每组各100例,观察组均为住院患者(双定位ESWL+间苯三酚),对照组均为门诊患者(单纯双定位ESWL),对比两组临床治疗效果、围手术期指标以及治疗前后hs-CRP水平情况。结果(1)对比两组输尿管结石患者的临床疗效,观察组综合疗效率(94.00%)明显高于对照组综合疗效率(82.00%),差异有统计学意义(P<0.05)。(2)对比两组输尿管结石患者的围手术期临床指标,观察组各项围手术期临床指标(结石排出时间、碎石次数、疼痛程度)均明显优于对照组,差异有统计学意义(P<0.05)。(3)对比两组输尿管结石患者的hs-CRP水平,治疗前,两组输尿管结石患者的hs-CRP水平比较差异无统计学意义(P>0.05);治疗后,两组患者hs-CRP水平均出现明显下降,且观察组明显低于对照组,差异有统计学意义(P<0.05)。结论双定位ESWL联合间苯三酚应用于输尿管结石临床治疗效果显著,可有效改善患者围手术期临床指标及hs-CRP水平,促进结石彻底清除,值得临床推广。

Objective To explore the treatment effect of combined therapy[double location extracorporeal shock wave lithotripsy(ESWL)+phloroglucinol]in patients with ureteral calculi and its influence on high sensitivity C-reactive protein(hs-CRP)level.Methods A total of 200 cases of patients with ureteral calculi and who treated in our hospital from January 2019 to February 2021 were selected,and the patients were divided into two groups according to the difference of treatment methods,with 100 cases in each group.The observation group were all hospitalized patients(double location ESWL+phloroglucinol),and the control group were all outpatients(simple double location ESWL).Then,the clinical effect,perioperative indexes and hs-CRP levels before and after treatment were compared between the two groups.Results(1)The clinical effect of two groups of patients with ureteral calculi were compared:the comprehensive treatment efficiency in the observation group(94.00%)was significantly higher than that in the control group(82.00%),and the difference was statistically significant(P<0.05).(2)The perioperative clinical indexes of two groups were compared:the perioperative clinical indexes in the observation group were significantly better than those in the control group,and the difference was statistically significant(P<0.05).(3)The hs-CRP levels of two groups were compared:there was no significant difference in hs-CRP level between the two groups before treatment(P>0.05).After treatment,the hs-CRP levels of two groups were significantly decreased,and the hs-CRP in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The clinical effect of double location ESWL combined with phloroglucinol in treatment of ureteral calculi is significant,which can effectively improve the perioperative clinical indicators and hs-CRP level,and promote the complete removal of calculi,thus it is worth promoting in the clinical.