独活寄生汤联合中医康复对膝关节骨性关节炎的治疗效果及血清炎性因子的影响

Therapeutic Effect of Duhuojisheng Decoction Combined with Traditional Chinese Medicine Rehabilitation on Knee Osteoarthritis and the Effect of Serum Inflammatory Factor

目的探究独活寄生汤联合中医康复应用于膝关节骨性关节炎治疗中的价值。方法选取2019年1月~2021年1月东营市第二人民医院康复医学科收治的100例膝关节骨性关节炎患者为研究对象,通过随机数表法分为试验组和对照组,各50例,对照组实施中医康复治疗干预,试验组则在对照组的基础上实施独活寄生汤治疗干预,分析两组膝关节骨性关节炎患者的治疗效果、膝关节功能、血清炎性因子水平及不良反应发生情况等的差异性。结果比较两组治疗总有效率,试验组高于对照组,差异有统计学意义(P<0.05);试验组治疗后膝关节功能评分低于对照组,差异有统计学意义(P<0.05);试验组治疗后血清炎性因子水平低于对照组,差异有统计学意义(P<0.05);比较不良反应发生率,试验组低于对照组,差异有统计学意义(P<0.05)。结论独活寄生汤联合中医康复治疗,可提高膝关节骨性关节炎患者的治疗效果,更好地改善其膝关节功能及血清炎性因子水平,且不良反应发生率低,安全有效。

Objective To explore the value of Duhuojisheng Decoction combined with traditional Chinese medicine rehabilitation in the treatment of knee osteoarthritis.Methods 100 patients with knee osteoarthritis admitted to the Department of Rehabilitation Medicine of Dongying Second People’s Hospital from January 2019 to January 2021 were selected as the Subjects of the study.They were randomly divided into test group and control group,with 50 cases in each group.The control group implemented TCM rehabilitation intervention,and the test group implemented Duhuojisheng Decoction on the basis of the control group.The treatment eff ect and knee function of the two groups of knee osteoarthritis patients were analyzed.Diff erences in the level of serum infl ammatory factors and the occurrence of adverse reactions were observed as well.Results Compared with the test group,the total eff ective rate was higher,and the diff erence was signifi cant(P<0.05);the knee joint function score of the test group after treatment was lower than that of the control group,and the diff erence was statistically signifi cant(P<0.05);the serum infl ammatory factor level after treatment in the test group was lower than that of the control group,and the diff erence was statistically signifi cant(P<0.05);Compared with the test group,the incidence of adverse reactions was lower,and the diff erence was statistically signifi cant(P<0.05).Conclusion Duhuojisheng Decoction combined with traditional Chinese medicine rehabilitation treatment can improve the treatment eff ect of patients with knee osteoarthritis,knee joint function and serum infl ammatory factor levels,and the test grap has a lower incidence of adverse reactions,which is safe and eff ective.