血清铁蛋白、尿酸表达与非酒精性脂肪肝患者预后的相关性

Correlation between the Serum Ferritin and Uric Acid Expression and the Prognosis of Patients with Nonalcoholic Fatty Liver Disease

目的分析血清铁蛋白(SF)、尿酸(UA)表达与非酒精性脂肪肝(NAFLD)患者预后的关系。方法回顾性分析2019年1月至2020年12月我院收治的88例NAFLD患者的临床资料,统计患者预后情况,并分析SF、UA表达与NAFLD患者预后的关系。结果88例NAFLD患者中预后不良30例,占34.09%;预后良好58例,占65.91%。预后不良与预后良好患者的性别、年龄、病程及BMI比较差异无统计学意义(P>0.05);预后不良患者的SF、UA水平高于预后良好患者(P<0.05)。绘制ROC曲线图结果显示,SF、UA水平预测NAFLD患者预后的AUC>0.70,预测价值均理想,且以联合预测价值最佳。结论SF、UA表达与NAFLD患者预后有关,联合预测有助于判断NAFLD患者预后情况。

Objective To analyze the correlation between the serum ferritin(SF)and uric acid(UA)expression and the prognosis of patients with nonalcoholic fatty liver disease(NAFLD).Methods The clinical data of 88 NAFLD patients admitted to our hospital from January 2019 to December 2020 were retrospectively analyzed,and their prognosis was counted.The correlation between the SF and UA expression and the prognosis of NAFLD patients was analyzed.Results Among 88 NAFLD patients,30 cases had poor prognosis,accoxmting for 34.09%;58 cases had good prognosis,accounting for 65.91%.No statistical difference was found in the gender,age,disease course and BMI between the patients with poor prognosis group and the patients with good prognosis(P>0.05).The SF and UA levels of patients with poor prognosis group were higher than those of patients with good prognosis(P<0.05).ROC curve results showed that the AUC of SF and UA in predicting the prognosis of NAFLD patients was>0.70,the predictive value was ideal,and the combined predictive value was the best.Conclusions The expression of SF and UA is related to the prognosis of NAFLD patients,and the combined prediction is helpful to judge the prognosis of NAFLD patients.