急性胰腺炎:预后标志物的研究进展

Acute pancreatitis:progress in evaluation of prognostic markers

急性胰腺炎(acute pancreatitis,AP)是一种常见的消化系统疾病。虽然大部分呈自限性病程,但重症急性胰腺炎(severe acute pancreatitis,SAP)患者仍有较高的死亡率,因此,早期评估患者病情,给予有效治疗,有助于改善患者预后。传统评分系统的临床应用价值仍不确定,且耗时、繁琐,限制了其临床应用。因此,临床亟需操作简单快速、灵敏度高的评估方法。近年来,研究发现临床常用实验室指标亦有较高预测价值,且操作简单、快速,本文旨在概述实验室指标在AP预后评估中的临床应用价值。

Acute pancreatitis(AP)is a common disease of the digestive system.Although the majority of patients have a self-limited course,there is still a high mortality rate in patients with severe acute pancreatitis(SAP),so early assessment of the patient′s condition can help improve the prognosis of patients.The clinical application value of traditional scoring system is still uncertain,and it is time-consuming and cumbersome,which limits its clinical application.Therefore,simple,rapid and sensitive evaluation methods are urgently needed in clinical practice.In recent years,it has been found that commonly used laboratory indicators also have high predictive value,and the operation is simple and rapid.This paper aimed to review the clinical application value of laboratory indicators in the prognosis assessment of AP.