摘要
目的:探讨腹针与头针治疗原发性失眠患者的临床效果。方法:将2018年1月—2020年6月我院收治的150例原发性失眠患者观察对象,遵循随机数字表法的分组原则将其均分为两组:观察组和对照组。对照组75例患者应用艾司唑仑片治疗,研究组75例患者在服用艾司唑仑片的基础上联合应用腹针与头针治疗,对两组的临床治疗效果进行比较,比较治疗前后匹兹堡睡眠质量指数(PSQI)、失眠严重指数(ISI),检测比较两组治疗前后血清GABA(γ-氨基丁酸)、COR(皮质醇)、5-HT(5-羟色胺)水平。结果:治疗后两组MMSE评分高于治疗前,NPI评分低于治疗前(P<0.05)。研究组治疗后MMSE高于对照组,NPI评分低于对照组(P<0.05)。研究组的临床总有效率较对照组的显著提高(92.00%VS 80.00%),差异有显著性(P<0.05)。两组血清GABA以及5-HT水平治疗后均高于治疗前,COR水平低于治疗前(P<0.05)。研究组治疗后血清GABA及5-HT水平高于对照组,COR水平低于对照组(P<0.05)。结论:腹针与头针治疗原发性失眠患者的临床效果确切,患者的睡眠治疗明显好转,考虑机制可能与调节机体细胞因子水平有关。
Objective:To explore the clinical effect of abdominal acupuncture and scalp acupuncture on patients with primary insomnia.Methods:150 patients with primary insomnia treated in our hospital from January 2018 to June 2020 were divided into two groups according to the grouping principle of random number table:observation group and control group.75 patients in the control group were treated with estazolam tablets,and 75 patients in the study group were treated with abdominal acupuncture and scalp acupuncture on the basis of taking estazolam tablets.The clinical therapeutic effects of the two groups were compared,Pittsburgh sleep quality index(PSQI)and insomnia severity index(ISI)were compared before and after treatment,and serum GABA、Cortisol、5-hydroxytryptamine levels was detected and compared between the two groups before and after treatment.Results:after treatment,the MMSE score of the two groups was higher than that before treatment,and the NPI score was lower than that before treatment(P<0.05).After treatment,MMSE in the study group was higher than that in the control group,and NPI score was lower than that in the control group(P<0.05).The total clinical effective rate of the study group was significantly higher than that of the control group(92.00%VS 80.00%)(P<0.05).The levels of serum GABA and 5-HT in the two groups were higher than those before treatment,and the level of cor was lower than that before treatment(P<0.05).After treatment,the levels of serum GABA and 5-HT in the study group were higher than those in the control group,and the level of cor was lower than those in the control group(P<0.05).Conclusion:The clinical effect of abdominal acupuncture and scalp acupuncture in the treatment of patients with primary insomnia is accurate,and the sleep treatment of patients is significantly improved.The mechanism may be related to the regulation of the level of cytokines.
作者
康宁宁
Kang Ningning(Jinzhou Hospital ofTraditional Chinese Medicine,Jinzhou Liaoning 121000)
出处
《黑龙江医药》
CAS
2022年第2期413-415,共3页
Heilongjiang Medicine journal
关键词
腹针
头针
原发性失眠
治疗效果
睡眠质量
细胞因子
Abdominal needle
Head pin
Primary insomnia
Therapeutic effect
Sleep quality
Cell factor