以关节炎为首发表现的儿童EB病毒相关平滑肌肿瘤1例

Case report of Epstein-Barr virus-associated smooth muscle tumor in children with arthritis as the first manifestation

对2020年5月湖南省儿童医院肾脏风湿科收治的1例非人类免疫缺陷病毒(HIV)/移植相关的儿童EB病毒相关平滑肌肿瘤患儿的临床资料进行回顾性分析。患儿,女,6岁7个月,因"双侧髋关节疼痛1年余"就诊,影像学检查发现中枢神经系统及肺部多发结节灶,本例患儿早期无中枢神经系统及肺部病灶的定位性疼痛或器官功能障碍,而以关节炎为首发表现,因此被误诊为幼年特发性关节炎,最终经病理诊断为EB病毒相关平滑肌肿瘤,该病是与免疫抑制相关的一种罕见肿瘤。

Clinical data of a case of Epstein-Barr virus-associated smooth muscle tumor with non-human immunodeficiency virus/transplantation admitted in the Department of Nephrology and Rheumatology,Hunan Children′s Hospital in May 2020 were retrospectively analyzed.The 6 years and 7 months old girl presented with bilateral hip pain for more than 1 year.Imaging examination revealed multiple nodular lesions in the central nervous system and lungs.Arthritis was the first manifestation in this case,and as a result,the patient was misdiagnosed as juvenile idiopathic arthritis.Finally,the patient was pathologically diagnosed as Epstein-Barr virus-associated smooth muscle tumor,which was a rare tumor associated with immunosuppression.