慢性阻塞性肺疾病患者应用经鼻高流量湿化氧疗治疗的研究现状

Research status of nasal high flow humidification oxygen therapy for patients with chronic obstructive pulmonary disease

慢性阻塞性肺疾病对人类健康的威胁与日俱增,因此在临床上对其的重视程度也逐渐升高。临床上常采用氧疗来治疗慢性阻塞性肺疾病,主要通过抑制疾病恶化,帮助患者提高生存质量,同时降低其发生并发症的概率。但是,传统氧疗对于慢性阻塞性肺疾病的治疗效果相对较差。作为一种当今新型的氧疗方式,经鼻高流量氧疗可通过加高的流速对患者缺氧等状态进行改善,还可缓解患者二氧化碳潴留的情况,同时因其可对患者进行稳定的加湿及保温效果,从而增加患者在疾病治疗过程中的舒适感,极大程度缩短患者治疗时间,还可降低发生呼吸道感染和支气管痉挛的概率。本文就高流量氧疗湿化治疗仪的主要工作原理、临床性能、在稳定期慢性阻塞性肺疾病患者管理中的应用、在急性加重期慢性阻塞性肺疾病患者中的应用等进行研究,并做如下综述。

Chronic obstructive pulmonary disease poses an increasing threat to human health,so it has received increasing clinical attention.In clinic,oxygen therapy is often used to treat chronic obstructive pulmonary disease,which can help patients improve their quality of life and reduce the probability of complications by inhibiting the deterioration of the disease.However,the treatment effect of the traditional oxygen therapy on chronic obstructive pulmonary disease is relatively poor.As a novel oxygen therapy model,nasal high-flow oxygen therapy can improve the patients'state of hypoxia through a high flow rate,relieve their carbon dioxide retention conditions,and at the same time improve their comfort level during the disease treatment process due to stable humidification and heat preservation effects.It greatly shortens patients'treatment time and reduces the probability of respiratory tract infection and bronchospasm.This study focused on the main working principle,clinical performance,application in stable chronic obstructive pulmonary disease patients and acute exacerbation chronic obstructive pulmonary disease patients management of high flow oxygen therapy humidification therapeutic apparatus,and made the following review.