2013—2020年瓯海区居民恶性肿瘤死亡趋势及减寿分析

Trends in mortality and life lost due to cancer in Ouhai District from 2013 to 2020

目的了解2013—2020年温州市瓯海区居民恶性肿瘤死亡趋势和寿命损失情况,为制定恶性肿瘤防控策略提供依据。方法通过浙江省慢性病监测信息管理系统收集2013—2020年瓯海区居民恶性肿瘤死亡病例资料,计算粗死亡率、标化死亡率、潜在减寿年数(YPLL)、潜在减寿率(YPLLR)、标化潜在减寿年数(SYPLL)、标化潜在减寿率(SYPLLR)、平均减寿年数(AYLL)和年度变化百分比(APC),分析恶性肿瘤死亡趋势及寿命损失情况。结果2013—2020年瓯海区报告恶性肿瘤死亡5435例,粗死亡率为154.10/10万,标化死亡率为119.41/10万;男性粗死亡率为196.26/10万,高于女性的111.09/10万(χ^(2)=415.623,P<0.001)。全人群恶性肿瘤标化死亡率、男性粗死亡率和男性标化死亡率均呈下降趋势(P<0.05),APC值分别为-3.25%、-2.18%和-4.78%。恶性肿瘤粗死亡率随年龄增长呈上升趋势(χ_(趋势)^(2)=9260.583,P<0.001)。恶性肿瘤死亡顺位前五位依次为肺癌、肝癌、胃癌、结直肠癌和食管癌,占恶性肿瘤死亡的66.68%。寿命损失顺位前五位依次为肝癌、肺癌、胃癌、结直肠癌和脑肿瘤,YPLL分别为11191.50人年、8231.00人年、6000.00人年、3892.00人年和2693.50人年。白血病居AYLL首位,为25.17年/人。结论2013—2020年瓯海区恶性肿瘤标化死亡率和寿命损失均呈下降趋势,男性和老年人为高危人群。肺癌、肝癌、胃癌、结直肠癌、白血病、脑肿瘤和女性乳腺癌为瓯海区恶性肿瘤防治重点。

Objective To investigate the trends in mortality and life lost due to cancer among residents in Ouhai District,Wenzhou City from 2013 to 2020,so as to provide the evidence for formulating the cancer control strategy.Methods The mortality data of cancer patients in Ouhai District from 2013 to 2020 were collected through Zhejiang Provincial Information Management System for Surveillance of Chronic Diseases.The crude mortality,standardized mortality,years of potential life lost(YPLL),years of potential life lost rate(YPLLR),standardized years of potential life lost(SYPLL),standardized years of potential life lost rate(SYPLLR).average years of life lost(AYLL)and annual percent change(APC)were estimated to analyze the trends in mortality and life lost due to cancer.Results Totally 5435 deaths occurred due to cancer in Ouhai District from 2013 to 2020,and the crude and standardized mortality rates were 154.10/10^(5)and 119.41/10^(5),respectively.The crude mortality of cancer was higher in men than in women(196.26/10^(5) and 111.09/10^(5);χ^(2)=415.623,P<0.001).The standardized mortality of cancer among whole populations,the crude mortality in men and the standardized mortality in men showed a tendency towards a reduction(P<0.05),with APC of-3.25%,-2.18% and-4.78%,respectively.The crude mortality of cancer showed an upward trend with age(χ_(trend)^(2)=9260.583,P<0.001).Lung cancer,liver cancer,stomach cancer,colorectal cancer and esophagus cancer were the five leading causes of cancer-related mortality,which accounted for 66.68%of all cancer mortality.Liver cancer,lung cancer,stomach cancer,colorectal cancer and brain cancer were the five leading causes of life lost,with YPLL of 11191.50,8231.00,6000.00,3892.00 and 2693.50 person-years,respectively.Leukemia was the primary cause of AYLL(25.17 years per person).Conclusions Both the standardized mortality and the life lost due to cancer showed a tendency towards a reduction in Ouhai District from 2013 to 2020,and men and the elderly were high-risk populations.Lung cancer,liver cancer,stomach cancer,colorectal cancer,leukemia,brain cancer,and female breast cancer should be listed among cancers in Ouhai District prioritized for control.