阿司匹林+氯吡格雷在老年冠心病患者中的治疗效果分析

Treatment effect of aspirin + clopidogrel in elderly patients with CHD

目的:探讨阿司匹林+氯吡格雷在老年冠心病患者中的治疗效果分析。方法:回顾性分析在我院接受治疗的老年冠心病患者临床资料,于2017年1月至2018年8月期间收治的病例中选取100例,所有患者信息均输入Excel表格进行编号,按照编号单双分为两组,其中50例序号为单数者采用阿司匹林治疗,作为对照组,50例序号为双数者在此基础上采用氯吡格雷治疗,作为观察组,使用SPSS17.0软件比较两组患者治疗效果。结果:观察组治疗总有效率为96.00%,与对照组为82.00%相比差异显著(P<0.05);治疗前,观察组血小板聚集率(PAG)、凝血酶原时间(PT)、凝血酶原活动度(PA)、活化部分凝血时间(APTT)等凝血指标以及心功能指标均无显著差异(P>0.05);治疗后,观察组上述指标均显著优于对照组(P<0.05);不良反应发生率:观察组(6.00%)显著低于对照组(20.00%),差异显著(P<0.05)。结论:采用阿司匹林+氯吡格雷治疗老年冠心病患者,可明显改善临床症状与凝血功能,安全性高。

Objective:To investigate the therapeutic effect of aspirin + clopidogrel in elderly patients with coronary heart disease.Methods:Retrospective analysis of the clinical data of elderly CHD patients treated in our hospital,from January 2017 to August 2018,all patients information are input into Excel form number,according to the number into two groups(50 cases),50 cases with serial number with aspirin treatment,as a control group,50 patients with clopidogrel,as the observation group,using SPSS17.0 software to compare the treatment effect of two groups.Results:The total treatment efficiency was 96.00% and significantly different compared to 82.00%(P<0.05);platelet aggregation rate(PAG),prothrombin time(PT),PA activity(PA),activated partial coagulation time(APTT)(P>0.05) before treatment,the observation group were significantly better than control(P<0.05);the incidence of adverse reactions:observation(6.00%) than control(20.00%)(P<0.05).Conclusion:The treatment of aspirin + clopidogrel in elderly patients can significantly improve the clinical symptoms and coagulation function with high safety.