摘要
Rabies is an ancient zoonotic disease first recorded over 4,000 years ago.Globally,over 99%of human rabies cases were caused by rabid dogs.Rabies is fatal once symptoms appear.However,rabies is preventable through mass dog vaccination and post-exposure prophylaxis(PEP),including wound treatment,vaccine injection,and passive immunization when necessary.Sustained vaccination coverage of 70%among dog populations can interrupt dogmediated rabies and is regarded as a first-line defense against human rabies for its cost-effectiveness.