摘要
数字光处理生物3D打印技术由于其特殊的成型原理,可以制造十分复杂的结构,近年来受到诸多学者的关注与研究。在世界各地多个交叉学科团队的努力下,其在打印质量、精度以及效率方面都取得了较大的突破。与此同时,具有生物相容性、可降解性以及生物活性的光固化材料的开发和细胞学的进步,也为这种打印技术在生物医学领域的广泛应用奠定了基础。本文对生物3D打印基本概念及原理进行了介绍,并分析了数字光处理技术的优点与劣势,综述了数字光处理生物3D打印技术在医学和转化医学领域的应用及前景。
Because of its special forming principle,digital light procession 3D bioprinting technology can produce very complex structure,which has been concerned and studied by many scholars in recent years.Thanks to the efforts of many interdisciplinary teams around the world,it has made great breakthroughs in printing quality,accuracy and efficiency.At the same time,the development of photocuring-based materials with biocompatibility,degradability and bioactivity and the progress of cytology have laid the foundation for the wide application of this printing technology in the biomedical field.In this paper,the basic concept and principle of 3D bioprinting was briefly describes.The advantages and disadvantages of digital light procession were analyzed.It also was summarized to the application and prospect of digital light procession 3D bioprinting technology in the field of medicine and transformed medicine.
作者
王赞
王浩
李德玲
石国宏
王金武
WANG Zan;WANG Hao;LI De-ling;SHI Guo-hong;WANG Jin-wu(College of Mechanical&Electrical Engineering,Henan University of Technology,Zhengzhou 450001,China;City University of ZhengZhou,Intelligent Manufacturing College,Zhengzhou 450001,China;Department of Orthopedics Surgery,Shanghai Ninth People’s Hospital,Shanghai JiaoTong University School of Medicine,Shanghai 200011,China)
出处
《数字印刷》
CAS
北大核心
2022年第2期14-22,共9页
Digital Printing
基金
国家科技部重点研发计划项目(No.2018YFB1105600/2018YFA0703000)
国家自然科学基金(No.82072412/81772326)
上海市科委项目(No.19XD1434200/18431903700)
上海交通大学医学院地高大双百人计划(No.20152224)
转化医学国家重大科技基础设施(上海)开放课题基金(No.TMSK-2020-118)
河南省教育厅重点基础研究项目(No.119A460012)
河南省科技厅自然科学项目(No.202102310552)
河南工业大学“省属高校基本科研业务费专项资金”项目(No.2017QNJH26)。
关键词
生物3D打印
光固化生物3D打印
增材制造
组织工程
数字光处理
3D bioprinting
Photocuring-based 3D bioprinting
Additive manufacturing
Tissue engineering
Digital light procession