摘要
随着对天然药物抗肿瘤作用机制研究的深入,发现其抗肿瘤作用可能与调节机体免疫功能,抑制肿瘤细胞的增殖、迁移、侵袭,逆转肿瘤细胞的多药耐药性,抑制端粒酶活性等相关。本文对天然药物抗肿瘤作用机制进行简要综述。
With the deepening of the research on the anti-tumor mechanism of natural products, it is found that their anti-tumor effects may be related to regulation of the body’s immune function, inhibition of the proliferation, migration and invasion of tumor cells, reverse of the multidrug resistance of tumor cells, and inhibition of the telomerase activity,etc. In this paper, the anti-tumor mechanism of natural drugs is briefly reviewed.
作者
房淼
王德刚
刘培庆
FANG Miao;WANG De-gang;LIU Pei-qing(School of Pharmaceutical Science,Sun Yat-sen University,Guangzhou 510006,China;Zhuhai United Laboratories Co.,Ltd.,Zhuhai 528467,China)
出处
《食品与药品》
CAS
2022年第2期167-171,共5页
Food and Drug
基金
国家自然科学基金资助项目(编号:81872860)
国家重大新药创制专项(编号:2019ZX09301104)
广东省“珠江人才计划”本土创新科研团队(编号:2017BT01Y093)。
关键词
抗肿瘤
天然药物
细胞分化
耐药性
免疫调节
anti-tumor
natural product
cell differentiation
drug resistance
immunomodulation