高原地区青中年人群睡眠与慢性病共病的关联

Association of sleep with chronic comorbidities of young and middle-aged people in a plateau area

目的探讨高原地区青中年人群睡眠时长、睡眠质量、睡眠打鼾和慢性病共病的关联。方法2018年5月―2019年8月采用多阶段随机整群抽样方法抽取拉萨市城关区30岁及以上人群进行问卷调查,采用多因素Logistic回归分析模型分析睡眠与慢性病共病之间的相关性。结果共纳入5505名30~<60岁青中年人,年龄为(44.70±8.50)岁,慢性病共病者占29.5%。多因素Logistic回归分析模型显示,在调整潜在混杂因素后,睡眠时长过短、睡眠质量差和睡眠打鼾是青中年人群慢性病共病的危险因素。与睡眠时长8 h相比,睡眠时长≤6 h者慢性病共病的OR值为1.57(95%CI:1.21~2.04);与睡眠质量好者相比,睡眠质量差者慢性病共病的OR值为1.59(95%CI:1.39~1.82);与睡眠时不打鼾者相比,睡眠时偶尔打鼾和经常打鼾者慢性病共病的OR值为1.20(95%CI:1.02~1.41)和1.64(95%CI:1.37~1.97)。结论睡眠时长过短(≤6 h)、睡眠质量差和睡眠打鼾与高原地区青中年人群慢性病共病风险相关。高原地区青中年人群不仅要保证适宜的睡眠时间,而且要控制睡眠打鼾行为,提高睡眠质量。

Objective To investigate the relationship of sleep duration,sleep quality,and snoring with chronic comorbidities in young and middle-aged people at high altitude.Methods From May 2018 to August 2019,people aged 30 and above in Chengguan District of Lhasa City were selected by multi-stage random cluster sampling method for questionnaire survey.Multivariate Logistic regression model was used to analyze the correlation between sleep and chronic comorbidities.Results A total of 5505 young and middle-aged people aged 30-59 years old were included in the study.The average age was(44.70±8.50)years old,and 29.5%of them were defined with chronic comorbidities.Multivariate Logistic regression models showed that shorter sleep duration,poor sleep quality,and snoring were risk factors for chronic comorbidities in young and middle-aged people after adjusting for potential confounding factors.Compared with participants with 8 hours of sleep duration daily,the OR(95%CI)of chronic comorbidities for those with sleep duration≤6 h was 1.57(95%CI:1.21-2.04).The OR(95%CI)of chronic comorbidities was 1.59(95%CI:1.39-1.82)in the poor sleep quality group compared with those with good sleep quality.Compared with those who did not snore during sleep,the OR(95%CI)of chronic comorbidities in those who snored occasionally and frequently during sleep were 1.20(95%CI:1.02-1.41)and 1.64(95%CI:1.37-1.97),respectively.Conclusions Shorter sleep duration(≤6 h),poor sleep quality,and snoring are associated with chronic comorbidities in young and middle-aged people at high altitude.The middle-aged people in plateau area should not only ensure the proper sleep time,but also control the snoring behavior and improve the sleep quality.