前列腺潜伏癌的尸检研究

Autopsy studies of latent prostate cancer

通过尸检发现的前列腺癌也被称为前列腺潜伏癌。了解前列腺潜伏癌有助于全面认识前列腺癌,指导临床工作。现有的尸检研究提供了前列腺潜伏癌的患病率、Gleason评分、肿瘤体积、前列腺包膜外侵犯以及空间分布等重要信息。然而,不同的研究在研究时间、人群、研究方法以及结果呈现方面存在差异,使得整合这些结果较为困难。本文综述了目前前列腺潜伏癌的尸检研究结果,分析了尸检研究方法对结果的影响,提出了目前研究不足之处以及未来研究的方向。

Latent prostate cancer is defined as prostate cancer that was undiagnosed during life and then detected through autopsy.As a complement to clinical data of diagnosed prostate cancer,autopsy studies provide us with epidemiological and pathological characteristics of latent prostate cancer and facilitate our understanding of this disease.Though differences in time,population,methods,and reporting of results across studies exist,we managed to integrate findings of global autopsy studies on latent prostate cancer,analyze the effect of methodology on the results and propose deficiencies as well as directions for further research.