先天性肾脏和尿路畸形的环境因素研究进展

Advances in environmental factors of congenital renal and urinary abnormalities

先天性肾脏和尿路畸形受基因和环境因素的共同影响,其中环境因素属于可控因素,研究先天性肾脏和尿路畸形的环境因素将有利于预防其发生。本综述就有关先天性肾脏和尿路畸形的环境因素研究现状进行综述。主要包括:母体妊娠期疾病、妊娠期药物暴露、妊娠期不良生活方式、羊水含量、胎儿出生体重、胎儿性别、胎龄、胎次等因素。

Congenital renal and urinary abnormalities are affected by both genetic and environmental factors,among which environmental factors are controllable factors.The study of environmental factors of congenital renal and urinary tract abnormalities will help to prevent their occurrence.This article reviews the current situation of environmental factors related to congenital renal and urinary tract abnormalities.It mainly includes:maternal pregnancy disease,pregnancy drug exposure,pregnancy lifestyle,amniotic fluid content,fetal birth weight,fetal sex,gestational age,parity and other factors.