终生足球训练人员肌肉衍生RNA的基因表达谱分析

Expression profiling of human muscle-derived RNA in senior football training

在既往的社会学及人体科学研究中均指出足球是一种快乐、社交和大众化的体育活动,其用途广泛,对人体健康益处很大,长久以来仍有人对长期足球运动的益处持怀疑态度,为验证这一问题,从人体微观角度利用生物信息学进行基因表达谱分析。利用GEO数据库的基因芯片数据,通过GEO2R、String、Cytoscape 3.7.1、MevHeatMap 4.9.0等工具对数据进行生物信息学分析与研究。结果表明:共得到6个关键基因、8个有关的生物过程以及2个关键的代谢调节通路。长期甚至终生的足球训练与运动对人体基因蛋白的表达以及微循环具有调节作用,对人体的代谢与运动能力、形体与健康以及疾病抵抗能力均有明显的提升。

In the previous sociological and human science research,it has been pointed out that football is a happy,social and popular sports activity,which has a wide range of uses and great health benefits.For a long time,some people still doubt the benefits of long-term football.In this study,we used bioinformatics gene expression profiling to verify this problem from the human microscopic perspective.Using the gene chip data of the GEO database and bioinformatics analysis,the study was carried out on the data through GEO2R,String,Cytoscape 3.7.1,MevHeatMap 4.9.0 and other tools.The results showed that 6 key genes,8 related biological processes and two key metabolic regulation pathways were obtained.Long-term and even life-long football training and sports can regulate the expression of human gene protein and microcirculation,and can improve the body's metabolism and exercise ability,body and health and disease resistance.