摘要
ST段抬高型心肌梗死是常见的心血管急危重症,致死率和致残率高。尽早实现心肌再灌注可有效挽救濒死心肌,改善ST段抬高型心肌梗死患者的预后,冠状动脉内溶栓在实现再灌注过程中发挥重要作用。现从血栓形成的机制、溶栓剂分类、冠状动脉内正向溶栓、血栓抽吸、血栓抽吸联合冠状动脉内溶栓、冠状动脉内逆向溶栓及应用前景等方面展开综述。
ST-segment elevation myocardial infarction is a common emergent and critical cardiovascular disease with high mortality and disability rate.Early myocardial reperfusion can effectively save the dying myocardium and improve the prognosis of patients with ST-segment elevation myocardial infarction.Intracoronary thrombolysis plays an important role in the process of reperfusion.This article reviews the mechanisms of thrombogenesis,the classification of thrombolytic agents,intracoronary forward thrombolysis,thrombus aspiration,thrombus aspiration combined with intracoronary thrombolysis,intracoronary retrograde thrombolysis and its application prospect.
作者
周星儿
赵施皓
郭宇婷
金荣杰
王继航
王建
郭毅
田进文
沈明志
ZHOU Xing’er;ZHAO Shihao;GUO Yuting;JIN Rongjie;WANG Jihang;WANG Jian;GUO Yi;TIAN Jinwen;SHEN Mingzhi(The Second School of Clinical Medicine,Sourthen Medical University,Guangzhou 510000,Guangdong,China;Department of Cardiology,Hainan Hospital of PLA General Hospital,Sanya 572013,Hainan,China)
出处
《心血管病学进展》
CAS
2022年第3期229-231,240,共4页
Advances in Cardiovascular Diseases
基金
海南省重点研发计划(ZDYF2020123,ZDYF2019188,ZDYF2017096)。
关键词
ST段抬高型心肌梗死
心肌再灌注
溶栓剂
冠状动脉内溶栓
ST-segment elevation myocardial infarction
Myocardial reperfusion
Thrombolytic agents
Intracoronary thrombolysis
