不适当窦性心动过速的研究进展

Inappropriate Sinus Tachycardia

不适当窦性心动过速(IST)又称持续无休止性心动过速,临床上通常表现为持续性的窦性心动过速,无明确原因可循,24小时动态心电图提示窦性心动过速>15万次,夜间心率>100次/min。患者临床上通常表现为心慌、乏力和运动量下降,部分患者可发生心动过速依赖性心肌病而诱发心功能不全。目前IST的病因尚不清楚,有学者认为交感神经活性增加、副交感神经活性降低或窦房结功能异常均可能导致其发生。近年来,国内外有大量学者对IST进行研究,现根据相关文献的研究结果进行综述。

Inappropriate sinus tachycardia(IST)is also known as continuous and endless tachycardia,is usually manifested as continuous sinus tachycardia in clinic,and there is no clear reason to follow.The 24-hour sinus tachycardia of ambulatory electrocardiogram was more than 150000 times,and the nighttime heart rate was more than 100 times/min.The clinical manifestations of patients are palpitation,fatigue and decreased physical activity.Some patients can develop tachycardia dependent cardiomyopathy and induce cardiac insufficiency.At present,the etiology of IST is not clear,and some scholars believe that increased sympathetic nerve activity,decreased parasympathetic nerve activity or abnormal sinoatrial node function may lead to the occurrence of IST.In recent years,a large number of scholars at home and abroad have studied IST,and this paper reviews the results of relevant literature.