自体富血小板血浆凝胶在创面修复中的应用研究进展

Research progress on the application of autologous platelet-rich plasma gel in wound repair

创面修复是指由于致伤因素的影响导致机体组织受损后,通过再生、修复、重建受损组织的病理生理过程。富血小板血浆(PRP)中含有极其丰富的高浓缩性血小板以及少量的白细胞和纤维蛋白,能够利用机体各种生物功能,调节创面组织内多种生长因子的释放和细胞的生长与转移,进而加快推进创面愈合。本文中,就PRP促进各类创面修复的机制与临床实践进行综述,为PRP在创面修复应用中的进一步探索提供思路。

Wound repair is the pathophysiological process of regeneration,repair,and reconstruction of damaged tissues after the body has been damaged due to the influence of injury-causing factors.Platelet-rich plasma(PRP)enriched with highly concentrated platelets and small amounts of white blood cells and fibrin,can regulate the release of various growth factors and cell growth and transfer in wounds tissue using various biological functions of the body,accelerating wound healing.In this paper,the author reviews the mechanisms and clinical practice of PRP in promoting various types of wound repair to provide ideas for further exploration of PRP in wound repair application.