Assessment of plasma 12(S)-Hydroxyeicosatetraenoic acid as a biomarker to predict mortality in adults with severe trauma

To the Editor Identification upon admission of a group of patients with severe traumatic injury presenting with a higher risk of death is crucial in designing personalized treatment strategies[1].However,there are as yet limited biomarkers for the prediction of mortality in patients with traumatic injury.12(S)-Hydroxyeicosatetraenoic acid(12(S)-HETE),as a classic metabolite of arachidonic acid,was suggested to be a potential biomarker in brain injury[2]or subarachnoid hemorrhage[3].