2019~2020年婚检人群HBV感染及免疫状况分析

Analysis of HBV infection and immune status among pre-marital medical check-up population during 2019-2020

目的了解本地区婚检人群乙型肝炎病毒(HBV)感染及免疫状况,为乙型肝炎(乙肝)防控提供科学依据。方法3579例本地区参加婚检的体检者,采用胶体金法检测HBV血清学指标。结果3579例体检者中,乙肝表面抗原(HBsAg)阳性46例,阳性率为1.29%;不同性别HBsAg阳性率比较,差异无统计学意义(P>0.05)。乙肝表面抗体(HBsAb)阳性882例,阳性率为24.64%;不同性别HBsAb阳性率比较,差异无统计学意义(P>0.05)。乙肝的感染模式有5种,其中以HBsAg+乙肝e抗体(HBeAb)+乙肝核心抗体(HBcAb)阳性检出率最高,为41.30%。结论本地区婚检人群存在一定比例的HBV感染者和易感者,应加强防控。

Objective To understand the hepatitis B virus(HBV)infection and immunization status among the pre-marital medical check-up population in the region,so as to provide scientific basis for prevention and control of hepatitis B.Methods 3579 cases of pre-marital medical check-ups in this region were tested for HBV serological indicators by colloidal gold method.Results Among 3579 physical examinations,46 cases were positive for hepatitis B surface antigen(HBsAg),with a positivity rate of 1.29%.The difference was not statistically significant when comparing the HBsAg positivity rate of different genders(P>0.05).There were 882 positive cases of hepatitis B surface antibody(HBsAb),with a positivity rate of 24.64%;the difference was not statistically significant when comparing the HBsAb positivity rates of different genders(P>0.05).There were five modes of hepatitis B infection,among which HBsAg+hepatitis B e antibody(HBeAb)+hepatitis B core antibody(HBcAb)had the highest positive detection rate of 41.30%.Conclusion There are a certain proportion of HBV infected and susceptible people among pre-marital medical check-ups,and prevention and control should be strengthened.