妊娠期高血压疾病子痫前期病变程度对高危儿听力的影响

The effect of the degree of preeclampsia in pregnancy hypertension on hearing of high risk infants

目的 探讨妊娠期高血压疾病子痫前期(HDP)病变程度对高危儿听力的影响。方法 将母亲在妊娠期有(HDP)史的235例高危儿按妊娠期高血压疾病子痫前期(HDP)病变程度分为轻度组(125例)和重度组(110例),采用TEOAE和AABR进行听力筛查,并与母亲无妊娠期高血压疾病子痫前期(HDP)的新生儿(2815例)进行比较。结果 母亲无妊娠期高血压疾病(HDP)的新生儿的初筛未通过率为10.65%(300/2815),复筛未通过率为1.96%(7/357);母亲有轻度(HDP)的高危新生儿初筛未通过率为13.6.00%(17/125),复筛未通过率为6.25%(3/48);母亲有重度(HDP)的高危新生儿初筛未通过率为20.0%(22/110),复筛未通过率为14.6%(6/41)。听力初筛、复筛未通过率两两组间比较,差异均有统计学意义(P<0.01)结论 母亲患有重度(HDP)的高危儿听力损失检出率高,病变程度越重听力损失越大。

Objective To investigate the influence of the degree of preeclampsia(HDP) in hypertensive disorder complicating pregnancy on hearing of high-risk infants. Methods 235 high-risk infants whose mothers had a history of gestational hypertension(HDP) were divided into mild group(125 cases) and severe group(110 cases) according to the degree of preeclampsia(HDP). TEOAE and AABR were used for hearing screening, and compared with 2815 neonates whose mothers had no preeclampsia(HDP).Results The failure rate of the first screening was 10.65%(300/2815), and the failure rate of the second screening was 1.96%(7/357);The failure rate of the first screening was 13.6%(17/125), and the failure rate of the second screening was 6.25%(3/48);20.0%(22/110) and 14.6%(6/41) of high-risk newborns whose mothers had severe HDP failed to pass the first screening. There were statistically significant differences in the failure rate of hearing screening between the two groups(P < 0.01),Conclusion The higher the rate of hearing loss in high risk children with severe(HDP) was,the more severe the degree of pathological changes was, the greater the hearing loss.