肝细胞癌肺转移的治疗现状

Current status of the treatment of hepatocellular carcinoma with pulmonary metastasis

肝细胞癌(简称“肝癌”)是我国第2位肿瘤致死病因,肝外转移是其预后不良的重要原因。随着影像学技术的不断进步,肝癌合并肝外转移的发现率逐年上升,其中肺是最常见的肝外转移器官。肝癌肺转移患者情况复杂,处理起来十分棘手,治疗方式尚无定论,各类指南仅建议行系统治疗,但收效甚微。本文归纳总结了肝癌肺转移的各种治疗手段和研究现状,以期为患者提供最佳个体化的综合治疗策略,从而提高其生存获益。

Hepatocellular carcinoma(HCC)is the second leading cause of cancer-related death in China,and extrahepatic metastasis is an important reason for its poor prognosis.With the continuous progress of imaging technology,the detection rate of HCC with extrahepatic metastasis is increasing year by year,among which the lung is the most common extrahepatic metastatic organ.The situation of HCC patients with lung metastasis is complex,which is very difficult to deal with and the treatment mode is still inconclusive.All kinds of guidelines only recommend systematic treatment,but with little effect.In this paper,various treatments for lung metastasis of HCC are summarized in order to provide the best individualized comprehensive treatment strategy for patients,so as to improve their survival benefits.