摘要
吲哚及其衍生物是重要的有机合成中间体,广泛存在于天然产物、医药和农药等功能分子中。吲哚的官能化转化可以通过多种途径实现,如氧化、还原、亲核加成、氧化偶联等。文中主要综述了部分常见的吲哚N1和C2~C7的C(N)-H键选择性官能化。
Indole and its derivatives are important intermediates in organic synthesis and widely exist in natural products,pharmaceuticals and pesticides.The functionalization of indoles can be realized by many methods,such as oxidation,reduction,nucleophilic addition,oxidative coupling and so on.This paper mainly reviews the selective functionalization of N1 and C2~C7 of indoles.
作者
景珊珊
刘晋言
吴洁
吴明韦
杨雪
陈霞
Jing Shanshan;Liu Jinyan;Wu Jie;Wu Mingwei;Yang Xue;Chen Xia(School of Chemistry and Materials Engineering,Liupanshui Normal University,Liupanshu553004,China)
出处
《山东化工》
CAS
2022年第4期11-14,共4页
Shandong Chemical Industry
基金
六盘水师范学院省级大学生创新创业训练计划项目(20195201494、20195201495、S202010977015和S202010977030)
关键词
吲哚
官能化
选择性
indole
functionalization
selection
