睑缘切口与传统切口重睑术Meta分析

Meta-analysis of Double Eyelid Surgery with Parallel Palpebral Margin Incision and Traditional Double Eyelid Incision

目的:睑缘切开重睑术与传统切开重睑术的临床疗效的系统评价。方法:通过计算机分别检索Cochrane、EMbase、PubMed、Web of Science、中国知网、维普、万方数据库中收集有关睑缘切口与传统切口重睑术随机对照试验,采用Stata12、RevMan 5.3软件对纳入文章进行Meta分析,选择文章以满意度、重睑弧度、线性瘢痕为Meta分析的评价指标。结果:共纳入10篇相关文献,总共有1147例患者,其中睑缘切开患者635例,普通切开患者512例。Meta分析显示,睑缘切口与传统切口重睑术患者满意度之间存在相关性[OR=2.44,95%CI(1.61,3.69),P<0.0001];重睑弧度[OR=0.58,95%CI(0.12,2.82),P=0.50];重睑切口线性瘢痕[OR=0.13,95%CI(0.05,0.34),P<0.0001]。结论:睑缘上切口重睑术在重睑满意度、降低瘢痕发生率明显优于传统切口重睑术,但是在重睑弧度流畅、自然方面两组差异无显著意义。

Objective To evaluate the clinical therapeutic effects of parallel palpebral margin incision and traditional double eyelid incision double eyelid surgery.Methods The databases of PubMed,Cochrane,Embase,Web of Science,CNKI,VIP and Wanfang were searched by computer.RCT of palpebral margin and traditional eyelid double eyelid incision were collected for quality evaluation and data extraction.The three indexes of patient satisfaction,double eyelid radian and scar were selected as evaluation indexes for the Meta-analysis.Two researchers independently screened the literature,extracted the data,and evaluated the risk of bias in the included studies.Then STATA12 and RevMan 5.3 software were used for statistical analysis.Results A total of 10 relevant research literature were included,including 1147 patients,including 635 patients with eyelid incision and 515 patients with general incision.Meta analysis showed that there was a correlation between patients’satisfaction with eyelid incision and traditional double eyelid incision[OR=2.44,95%CI(1.61,3.69),P<0.0001].Double eyelid radian[OR=0.58,95%CI(0.12,2.82),P=0.50].Linear scar of double eyelid incision[OR=0.13,95%CI(0.05,0.34),P<0.0001].Conclusion The results showed that palpebral margin incision was better than traditional double eyelid incision in double eyelid satisfaction and reducing the incidence of linear scar,and there was no significant difference in double eyelid radian fluency between the two groups.