缺血性卒中后睡眠质量对老年人认知功能的影响

Effect of Sleep Quality on Cognitive Function in the Elderly After Ischemic Stroke

目的缺血性卒中后睡眠质量对老年人认知功能的特征性分析。方法将纳入缺血性卒中后慢性失眠患者105例,采用匹兹堡睡眠质量指数(PSQI)评估受试者的失眠程度(部分慢性失眠患者接受问卷调查),采用蒙特利尔认知评估量表(MoCA)评估总体认知功能,分为缺血性卒中后睡眠认知障碍非痴呆(PSCI-ND)组45例和脑卒中后非认知障碍组(非PSCI)组60例。认知功能评估采用蒙特利尔认知评估量表(MoCA),记录日常生活活动能力量表(ADL),并收集相关临床资料,进行比较分析。结果PSCI-ND组受教育年限明显低于非PSCI组(P<0.05)。PSCI-ND组年龄明显高于非PSCI组(P<0.05)。PSCIND组ADL总分、MoCA总分明显低于非PSCI组[(86.80±10.52)分vs.(92.60±10.15)分,P=0.035;(17.05±4.25)分vs.(22.10±2.68)分,P=0.000]。PSCI-ND组睡眠行为障碍比例明显高于非PSCI组(P<0.05)。结论PSCI-ND组较易出现睡眠行为障碍、认知功能受损,揭示了睡眠障碍对老年人认知功能的影响。

Objective Characteristic analysis of the relationship between sleep quality and cognitive function in the elderly after ischemic stroke.Methods 105 patients with chronic insomnia after ischemic stroke were included.Pittsburgh sleep quality index(PSQI)was used to evaluate the degree of insomnia(some patients with chronic insomnia received questionnaire survey),and Montreal Cognitive Assessment Scale(MoCA)was used to evaluate the overall cognitive function of 105 patients.They were divided into two groups:non dementia group(psci-nd)with sleep cognitive impairment after ischemic stroke(n=45)and non cognitive impairment group(n=60).Montreal Cognitive Assessment Scale(MoCA)was used to assess cognitive function.Activities of daily living scale(ADL)was recorded and relevant clinical data were collected for comparative analysis.Results The education years of psci-nd group were significantly lower than those of non PSCI group(P<0.05).The age of psci-nd group was significantly higher than that of non PSCI group(P<0.05).The total scores of ADL and MOCA in psci-nd group were significantly lower than those in non PSCI Group[(86.8010.52)vs(92.6010.15),P=0.035;(17.054.25)vs(22.102.68),P=0.000].The proportion of sleep behavior disorder in psci-nd group was significantly higher than that in non PSCI group(P<0.05).Conclusion Psci-nd group is prone to sleep behavior disorder and cognitive impairment,which reveals the influence of sleep disorder on cognitive function of the elderly.