类风湿关节炎相关间质性肺病发病机制、诊断及治疗研究进展

Research progress in the pathogenesis,diagnosis and treatment of rheumatoid arthritis-related interstitial lung disease

类风湿关节炎(RA)是一种炎症性自身免疫疾病,主要影响关节还会影响其他身体组织。间质性肺病(ILD)是RA关节外表现较常见的一种疾病,可显著影响RA疾病的进展及预后。由于RA-ILD的致病因素及发病机制的复杂多样,以及缺乏特异性的诊断方法和明确的治疗手段,因此本文对RA-ILD的致病因素、发病机制、诊断及治疗的相关文献进行归纳与总结,以期为临床治疗提供参考。

Rheumatoid arthritis(RA)is an inflammatory autoimmune disease that mainly affects joints and other body tissues.Interstitial lung disease(ILD)is a common disease with extra-articular manifestations of RA,which can significantly affect the progression and prognosis of RA.Due to the complexity and diversity of the pathogenic factors and pathogenesis of RA-ILD,as well as the lack of specific diagnostic methods and clear treatment methods,this article summarizes the related literature on the pathogenic factors,pathogenesis,diagnosis and treatment of RA-ILD in order to provide reference for clinical treatment.