月月青化学成分研究

Study on the Chemical Constituents of Itea ilicifolia

[目的]阐明民族药月月青的化学成分。[方法]通过利用Sephadex LH-20、MCI gel、硅胶等多种柱色谱方法以及制备薄层法对月月青地上部分进行分离纯化,根据波谱数据并结合文献比对解析化学结构。[结果]从月月青中分离得到8个化合物,分别鉴定为植醇、丹皮酚、聚戊烯醇、1-十二醇、黑麦草内酯、单棕榈酸甘油酯、大黄素甲醚-8-O-β-D-葡萄糖苷、大黄素-8-O-β-D-葡萄糖苷。[结论]所有化合物均为首次从该植物中分离得到。

[Objective]To study the chemical constituents of Itea ilicifolia.[Method]Sephadex LH-20,MCI gel,silica gel column chromatography methods coupled with preparative thin-layer method were used to separate and purify compounds from the aerial part of Itea ilicifolia,and the chemical structure was elucidated based on spectral data and comparison with literature data.[Result]8 compounds were finally obtained and identified as phytol,paeonol,polyprenol,1-dodecanol,loliolide,glyceryl monopalmitate,physclon-8-O-β-D-glucopyranoside,emodin-8-O-β-D-glucopyranoside,respectively.[Conclusion]All compounds are identified from this plant for the first time.