前列腺癌的影像学诊断方法及PET/CT显像剂应用进展

Advances in imaging diagnosis of prostate cancer and the application of PET/CT imaging agents

近些年,我国前列腺癌(PCa)的发病率及病死率逐渐增高,并且PCa的早期诊断及准确分期仍是一大难题,多数患者确诊时已为晚期,生存预后较差。目前,MRI、CT、PET/CT等影像学检查方法是对PCa进行诊断及分期的主要手段,但这些方法在应用的过程中亦被发现存在一定的局限性,因此需要不断进行探索和优化。尤其是PET/CT各种显像剂的应用,大大提高了对PCa的诊断灵敏度及特异度,在PCa的早期诊断、及时治疗、临床分期及预后评估等各方面均展示出良好的前景。笔者就这几种常用影像学方法及PET/CT显像剂的应用展开综述,总结它们的优势、不足及新的应用进展,旨在能为临床医师提供参考。

In China,the incidence and mortality of prostate cancer(PCa)are increasing gradually,and the early diagnosis and accurate staging of PCa patients is still a major problem.Therefore,most patients have been diagnosed with advanced stage,leading to poor survival prognosis.MRI,CT,PET/CT and other imaging examinations are currently the main means for the diagnosis and staging of PCa,but these methods have also been found to have certain limitations,so they are constantly being explored and optimized.In particular,the application of various imaging agents in PET/CT has greatly improved the diagnostic sensitivity and specificity of PCa and shows a good prospect in the early diagnosis,timely treatment,clinical staging and prognosis evaluation of PCa.In this paper,these common imaging methods and PET/CT imaging agents are discussed;their advantages,disadvantages and new application progress are summarized,hoping to provide references to clinicians.