Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?

Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis(TB)in endemic regions including India,which has contributed the most to global TB burden.We argue here that a personalized medicine approach,to start with the N-acetyl transferase-2–isoniazid(NAT2–INH)model,could be a step forward in dealing with both these limitations in controlling TB in India.