基于CiteSpace对红细胞贮存损伤的发展态势和热点前沿分析

Development trend and research hotspots and frontiers of RBC storage lesion based on CiteSpace

目的了解红细胞贮存损伤研究领域的现状、热点、发展态势与前沿。方法登录Web of Science核心合集数据库(http://webofscience.com),以“红细胞贮存损伤”为关键词,以2005年-2021年为时限,检索其中收录的发表的有关红细胞贮存损伤的文章,不限文章类型,排除与红细胞贮存损伤内容无关的文章后,用CiteSpace(CiteSpace.5.7.R2)等统计学软件做文献计量学分析,包括“作者”(文章所有署名者)、(文章所属)“机构”和“国家”、期刊、关键词以及施引文献等指标。结果最终共纳入508篇文献,占此时段全部“红细胞贮存损伤”的91.86%(508/553);发文数年均增长率为14.38%。508篇文献共有1868名作者,发文量≥3篇的作者占39.76%(202/508),其中美国的D′alessandro A发文数第一[占7.68%(39/508)],Univ Colorado System和Univ Pittsburgh是发文数排前2位的机构[分别占7.28%(37/508)、7.09%(36/508)]。美国[占53.35%(271/508)]、加拿大[占13.19%(67/508)]、英国[占6.50%(33/508)]、瑞士[占6.10%(31/508)]是发文数居前的国家。关键词共现网络、突现图谱和文献共被引聚类图谱的词和聚类主要集中在机制研究、临床试验、改进红细胞贮存条件以及减少红细胞贮存损伤等方面。结论过去17年红细胞贮存损伤研究领域里重要的研究者、机构主要出自美欧国家;代谢组学等技术应用、红细胞贮存损伤机制探讨以及供体多样性选择、新型保存液或添加剂的研发是该领域的研究热点或前沿课题。

Objective To explore the research status,hotspots,development trend and frontier of RBC storage lesion.Methods The Web of Science core collection database(http://webofscience.com)was used to retrieve the documentsrelated to"red blood cell storage lesion"from 2005 to 2021.Af-ter the exclusion of unrelated documents,CiteSpace(CiteSpace.5.7.R2)was used for bibliometric analysis,including author(all signatories of the article),institution and country(to which the article is affiliated),journal,key words and cited literatures.Results A total of 508 literatures were included,account-ing for 91.86%(508/553)of all publication concerning"RBC storage lesion"in this period.The annual growth rate of pub-lications was 14.38%.There were 1868 authors totally,and 39.76%(202/508)of them published more than 3 papers.D′Alessandro A from the United States ranked first[7.68%(39/508)],Univ Colorado System and Univ Pittsburgh were thetop two institutions[7.28%(37/508)and 7.09%(36/508),respectively].The United States[53.35%(271/508)],Canada[13.19%(67/508)],the United Kingdom[6.50%(33/508)]and Switzerland[6.10%(31/508)]were the top4 countries.Keywords co-occurrence network,emergent atlas and literature co-citation cluster atlas mainly focused on mecha-nism research,clinical trials,improvement of RBC storage conditions and reduction of RBC storage lesion.Conclusion Themost important researchers and institutions in the field of RBC storage lesion in the past 17 years were mainly from the UnitedStates and Europe.The application of metabolomics and other technologies,the mechanism of RBC storage lesion,the selec-tion of donor diversity,and the research and development of new preservation solutions or additives are the hotspots and fron-tiers in this field.