QCT测定中年女性肝脏脂肪含量、腰椎骨密度与腹内脂肪和血糖的相关性分析

目的探讨中年女性肝脏脂肪含量、腰椎骨密度(BMD)与腹内脂肪、血糖之间的相关性。方法选取本院体检行QCT腰椎骨密度、肝脏脂肪含量、腹部脂肪面积检查的中年女性体检者153例,年龄40〜55岁。计算肝脏脂肪含量、腰椎骨密度与腹内脂肪面积、血糖的相关性系数,比较其相关性。结果Spearman相关分析结果显示,肝脏脂肪含量与腹内脂肪面积呈正相关(r=0.653,P<0.001),肝脏脂肪含量与血糖呈正相关(r=0.246,P=0.002)。腰椎骨密度与腹内脂肪面积呈负相关(r=-0.460,P<0.001),腰椎骨密度与血糖呈负相关(r=-0.110,P<0.002)。结论中年女性腹内脂肪含量是骨质疏松、脂肪肝的重影响因素。血糖也与肝脏脂肪含量及腰椎骨密度有相关性。

Objective To investigate the correlation between liver fat content,lumbar bone mineral density(BMD)and abdominal fat,blood glucose in middle-aged women.Methods A total of 153 middle-aged female physical examinees,aged 40-55,were selected from our hospital for QCT lumbar bone mineral density,liver fkt content and abdominal fat area.The correhtion coefficients of liver fat content,lumbar bone mineral density,intraperitoneal fat area and blood glucose were calculated and compared.Results Spearman correlation analysis showed that there was a high positive correlation between liver fat content and retroperitoneal fat area(r=0.653,P<0.001),and a low positive correlarion between liver fat content and blood glucose(r=0.246,P=0.002).There was a moderate negative correlation between lumbar BMD and retroperitoneal fat area(r=0.460,P<0.001),and a low positive correlation between lumbar BMD and blood glucose(r=-0.110,P<0.002).Conclusion intraperitoneal fat content in middle-aged women is a major influencing factor of osteoporosis and fatty liver.Blood glucose was ako correlated with liver fat content and lumbar bone mineral density.